Dream another little dream

The first two DREAM5 2010 challenges are out, with two more planned for later.  The DREAM project, a.k.a. the Dialogue for Reverse Engineering Assessments and Methods (co-organized by Julio Saez Rodriguez, Sorger lab), aims to provide a rigorous way of testing which reverse-engineering algorithms do best when tested against previously unseen experimental data.  Challenges out today: (1) predict the binding specificity of peptide-antibody interactions; (2) predict the binding specificity of a transcription factor binding to a 35-mer probe.  Coming soon: (1) predict disease phenotypes and infer gene networks from systems genetics data; (2) infer simulated and in-vivo gene regulation networks.  You’ll need to sign up on the DREAM website to download the data for the challenges.  Good luck!